Which one?
H110 Pro BTC+ is probably a bit of overkill with 13 PCI-e slots as it gets more complicated with more cards and more issues especially with AMD cards and Windows, nVidia and Linux might be OK. Also a lot of power needed for 13 cards.
Z270 Pro4 I like, 5 PCI-e slots, 3x M.2 slots for WiFi module, SSD and I think you can use adopter from M.2 to PCI-e 1x slot as well so potentially could run 6-7 video cards off it.
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Currently 8less
2011 Q7 S Line 3.0TDI, 2016 Tesla Model S 90D
8 history:
2006 A8 Sport 4.2TDI quattro SOLD,
1997 S8, reached end of life with gearbox failure
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